dependence

Used in three different ways:

  1. physical dependence, a physiological state of adaptation to a specific psychoactive substance characterized by the emergence of a withdrawal syndrome during abstinence, which may be relieved in total or in part by readministration of the substance
  2. psychological dependence, a subjective sense of need for a specific psychoactive substance, either for its positive effects or to avoid negative effects associated with its abstinence
  3. one category of psychoactive Substance Use Disorder.

Excerpts with permission from Graham, Allan W. & Schultz, Terry K. (Editors) (American Society of Addiction Medicine): Principles of Addiction Medicine, 2nd Edition

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