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Clinical Capsule™

An innate daily fluctuation of physiologic or behavioral functions, including sleep-wake states generally tied to the 24-hour daily dark-light cycle. It sometimes occurs at a measurably different periodicity (e.g., 23 or 25 hours) when light and dark and other time cues are removed.*

*Reprinted with permission from: Culebras, Antonio Clinical Handbook of Sleep Disorders Hardcover © 1996 Butterworth-Heinemann