drug: fluvoxamine

• Clinical class: antidepressant, anti-obsessive/compulsive
• Action: Selective serotonin reuptake inhibitor
• Chemical class: 2-aminoethyl oxime ethers of aralkylketones
• CSA schedule: none
• DEA number: none
• MEDLINEplus^® Drug Information

U.S. Preparations:

• Fluvoxamine Maleate Tablets (Apotex) FDA approved: for treatment of obsessive/compulsive disorder
• Luvox^® (Solvay) FDA approved: for treatment of obsessive/compulsive disorder
  3.25.1997 pediatric
  U.S. Prescribing information
• Luvox^® CR (Solvay) FDA approved:
  2.28.2008 for treatment of social anxiety disorder and obsessions and compulsions in patients with Obsessive Compulsive Disorder
  U.S. Prescribing information

Preparations Outside U.S.:

• Avoxin, Depromel^®, Dumirox^®, Dumyrox, Faverin^®, Fevarin^®, Floxyfral^®, Maveral

Stephen Stahl's Clinical Pearls* (Consult your physician before making any change in your treatment.)

• Consider for mixed anxiety depression.
• FDA label in USA for OCD, approved in Europe for depression, generally well tolerated and effective in panic.
• May have a lower incidence of sexual dysfunction than other SSRIs
• Blocks metabolism of theophylin so reduce theophylin dose if given concomitantly.
• Some withdrawal effects, GI side effects.
• Consider avoiding in patients with multiple GI somatic complaints, and/or insomnia who wish to avoid sexual dysfunction.

*Reprinted with permission from: Stahl, Stephen M Psychopharmacology of Antidepressants Paperback 1997 Martin Dunitz, Ltd & Blackwell Science You cannot fully appreciate this book until you have seen the extraordinary illustrations of every aspect of this area of psychopharmacology and neurochemistry. Loaded with practical clinical "pearls."

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