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general paresis of the insane

(dementia paralytica, general paralysis, paralytic dementia)
Before Salvarsan (an arsenic compound) and penicillin were developed as effective treatments this late manifestation of tertiary cerebral neurosyphilis accounted for a substantial proportion of the residents in mental hospitals. Now rare it is classified as a Mental Disorder Due to a General Medical Condition whose manifestations include Dementia and other symptoms.

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