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Paul Bettany, Jennifer Connelly, Jeremy Northam
ethyl alcohol-powdered opium
Spoiler alert
Blog entry

Scientist Charles Darwin thinks to himself how best to address his own symptoms: "Consider increasing laudanum by 10% perhaps." (0:10)

Charles' deceased daughter Annie appears to him. (0:27, 0:51, 1:01, 1:18, 1:41)

Charles hallucinates. (0:57)

Charles encounters his wife Emma for the first time after Annie's death. (1:14)

Charles talks with Dr. Gully who asks him about his familiarity with the works of (presumably Thomas Confessions of an English Opium Eater) "De Quincey... He maintains that certain thoughts can reside in our mind without us being aware of them. They then may manifest as boils and fainting spells, and ghosts." (1:16) Did De Quincey actually formulate early theories of unconscious production of physical (somatization) or mental symptoms or pathology.

Annie dies with Charles at her bedside, and, back in the present, he cries. (1:25)