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Loss

In draft research domain criteria, a Construct of a Negative Valence System

"A state of deprivation of a motivationally significant con-specific, object, or situation. Loss may be social or non-social and may include permanent or sustained loss of shelter, behavioral control, status, loved ones, or relationships. The response to loss may be episodic (e.g., grief) or sustained."

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The National Institute of Mental Health Research Domain Criteria (RDoC)

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